YanXun V-Yu


Address: Bldg.#8, Room#1124         

              Medical Research Institute

              Wuhan University

              Wuhan, Hubei Province, P.R.China 430071


 Phone: +86-13618620150


2007 Ph.D Neuroscience, University of Illinois at Urbana-Champaign

1999 B.S. Microbiology and Immunology, Wuhan University, China


2018 – present Professor, Wuhan University, P.R.China

Research Experience

2011–2018  Postdoctoral fellow

                 Brandeis University, Lab of Piali Sengupta

2007–2011  Postdoctoral fellow

                 University of Rochester, Lab of Michael Welte

2000–2007  Pre-doctoral fellow

                 University of Illinois at Urbana-Champaign, Lab of Martha Gillette

1999-2000  Pre-doctoral fellow

                 Department of Microbiology, University of Illinois at Urbana-Champaign

1998 – 1999 Research assistant

                  Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, Lab of Zuo-yan Zhu


2018  Chinese government “The 1000 Talents Plan” for young professionals Award

2016  Travel award from Glenn Foundation for Medical Research for attending the course

Comparative and Experimental Approaches to Aging Biology Research” at MDI Biological Laboratory

2002  Graduate Teaching Certificate, University of Illinois

1998  Graduated with Honors, Wuhan University

Teaching experience

2007 Spring MCB 251 Experimental Techniques in Molecular Biology

2006 Spring MCB 250 Molecular Genetics

2005 Fall   MCB 250 Molecular Genetics

2005 Fall MCB 401 Cell and Membrane Physiology

2005 Spring MCB 253 Experimental Techniques in Cell Biology

2004 Fall MCB 251 Experimental Techniques in Molecular Biology

2002 Spring PHYSL 103 Introduction to Human Physiology Lab

2001 Fall PHYSL 103 Introduction to Human Physiology Lab

2001 Spring CSB 217 Experimental Techniques in Cellular and Molecular Biology

2000 Fall PHYSL 103 Introduction to Human Physiology Lab

Publications  (* denotes equal contribution)

Takeishi1 A*, Yu YV*, Hapiak VM, Bell HW, O’Leary T, Sengupta P.  Receptor-type guanylyl cyclases are thermosensory proteins in C. elegans. Neuron. (2016) 90:235

Yu YV*, Bell HW*, Glauser DA, Van Hooser SD, Goodman MB, Sengupta P.  CaMKI-dependent regulation of sensory gene expression mediates experience-dependent plasticity in the operating range of a thermosensory neuron. Neuron. (2014) 84: 919

Schild LC, Zbinden L, Bell HW, Yu YV, Sengupta P, Goodman MB, Glauser DA.  The balance between cytoplasmic and nuclear CaM kinase-1 signaling controls the operating range of noxious heat avoidance. Neuron. (2014) 84:983

Gaspar I*, Yu YV*, Cotton SL, Kim DH, Ephrussi A, Welte MA.  Klar ensures thermal robustness of oskar localization by restraining RNP motility. J Cell Biol. (2014) 206:199

Jin YN, Yu YV, Gundemir S, Jo C, Cui M, Tieu K, Johnson GV. Impaired mitochondrial dynamics and Nrf2 signaling contribute to compromised responses to oxidative stress in striatal cells expressing full-length mutant huntingtin. PLoS One. (2013) 8(3):e57932

Elhanany-Tamir H, Yu YV, Shnayder M, Jain A, Welte MA, Volk T.  Organelle positioning in muscles requires cooperation between two KASH proteins and microtubules. J Cell Biol. (2012) 198:833

Wang TA*, Yu YV*, Govindaiah G, Ye X, Artinian L, Coleman TP, Sweedler JV, Cox CL, Gillette MU. Circadian rhythm of redox state regulates excitability in suprachiasmatic nucleus neurons. Science. (2012) 337:839

Yu YV, Li ZH, Rizzo NP, Einstein J, Welte MA.  Targeting the Motor Regulator Klar to Lipid Droplets. BMC Cell Biol. (2011) 12:9

Invited Talks

2016 Department of Cell Biology, University of Connecticut Health Center

      “Receptor-type guanylyl cyclases : new insights into thermosenstion”

2014 BAWM (Boston Area Worm Meeting)

       A role for CaMKI in thermosensory adaptation

2014 C. elegans Neuro Meeting, Madison, Wisconsin

       CaMKI-mediated adaption to temperature in C. elegans


2015 C. elegans international meeting, Los Angeles, CA

        AFD-specific guanylate cyclases and CMK1-mediated thermosensory signaling in AFD.

2010 Annual meeting of the American Society for Cell Biology, Philadelphia, PAThe motor Regulator Klar Interacts Physically and Functionally with Kinesin-1 and Dynein in Drosophila Ovaries.

2004 Annual meeting of the Society for Neuroscience, San Diego, CA

        Redox State Modulates Directionality of Responses of the Suprachiasmatic

        Nucleus to Glutamate.

Tel: 0086-27-68750205 Fax: 0086-27-68759675  Email:

Contact address: Donghu Road, No. 115, Wuchang District, Wuhan, Hubei Province, P.R. China. 430071

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